Detalhe da pesquisa
1.
The BRCT Domains of the BRCA1 and BARD1 Tumor Suppressors Differentially Regulate Homology-Directed Repair and Stalled Fork Protection.
Mol Cell
; 72(1): 127-139.e8, 2018 10 04.
Artigo
Inglês
| MEDLINE | ID: mdl-30244837
2.
Abolishing the prelamin A ZMPSTE24 cleavage site leads to progeroid phenotypes with near-normal longevity in mice.
Proc Natl Acad Sci U S A
; 119(9)2022 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35197292
3.
Long-term vitamin A supplementation in a preclinical mouse model for RhoD190N-associated retinitis pigmentosa.
Hum Mol Genet
; 31(14): 2438-2451, 2022 07 21.
Artigo
Inglês
| MEDLINE | ID: mdl-35195241
4.
Mouse Models of Achromatopsia in Addressing Temporal "Point of No Return" in Gene-Therapy.
Int J Mol Sci
; 22(15)2021 Jul 28.
Artigo
Inglês
| MEDLINE | ID: mdl-34360834
5.
Parenchymal and stromal tissue regeneration of tooth organ by pivotal signals reinstated in decellularized matrix.
Nat Mater
; 18(6): 627-637, 2019 06.
Artigo
Inglês
| MEDLINE | ID: mdl-31114073
6.
Protective mucosal immunity mediated by epithelial CD1d and IL-10.
Nature
; 509(7501): 497-502, 2014 May 22.
Artigo
Inglês
| MEDLINE | ID: mdl-24717441
7.
Mechanisms of neurodegeneration in a preclinical autosomal dominant retinitis pigmentosa knock-in model with a RhoD190N mutation.
Cell Mol Life Sci
; 76(18): 3657-3665, 2019 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-30976840
8.
Genetic rescue models refute nonautonomous rod cell death in retinitis pigmentosa.
Proc Natl Acad Sci U S A
; 114(20): 5259-5264, 2017 05 16.
Artigo
Inglês
| MEDLINE | ID: mdl-28468800
9.
Genetic Rescue Reverses Microglial Activation in Preclinical Models of Retinitis Pigmentosa.
Mol Ther
; 26(8): 1953-1964, 2018 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30001913
10.
MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation.
Proc Natl Acad Sci U S A
; 113(23): 6526-31, 2016 Jun 07.
Artigo
Inglês
| MEDLINE | ID: mdl-27199481
11.
Reprogramming towards anabolism impedes degeneration in a preclinical model of retinitis pigmentosa.
Hum Mol Genet
; 25(19): 4244-4255, 2016 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27516389
12.
Clustered Regularly Interspaced Short Palindromic Repeats-Based Genome Surgery for the Treatment of Autosomal Dominant Retinitis Pigmentosa.
Ophthalmology
; 125(9): 1421-1430, 2018 09.
Artigo
Inglês
| MEDLINE | ID: mdl-29759820
13.
A Practical Approach to Retinal Dystrophies.
Adv Exp Med Biol
; 1085: 245-259, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-30578524
14.
Effects on murine behavior and lifespan of selectively decreasing expression of mutant huntingtin allele by supt4h knockdown.
PLoS Genet
; 11(3): e1005043, 2015 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-25760041
15.
Neurofilament light polypeptide gene N98S mutation in mice leads to neurofilament network abnormalities and a Charcot-Marie-Tooth Type 2E phenotype.
Hum Mol Genet
; 24(8): 2163-74, 2015 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25552649
16.
CAPN5 mutation in hereditary uveitis: the R243L mutation increases calpain catalytic activity and triggers intraocular inflammation in a mouse model.
Hum Mol Genet
; 24(16): 4584-98, 2015 Aug 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25994508
17.
PDGFRß-P2A-CreERT2 mice: a genetic tool to target pericytes in angiogenesis.
Angiogenesis
; 20(4): 655-662, 2017 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-28752390
18.
C/EBP-Homologous Protein (CHOP) in Vascular Smooth Muscle Cells Regulates Their Proliferation in Aortic Explants and Atherosclerotic Lesions.
Circ Res
; 116(11): 1736-43, 2015 May 22.
Artigo
Inglês
| MEDLINE | ID: mdl-25872946
19.
CRISPR Repair Reveals Causative Mutation in a Preclinical Model of Retinitis Pigmentosa.
Mol Ther
; 24(8): 1388-94, 2016 08.
Artigo
Inglês
| MEDLINE | ID: mdl-27203441
20.
Therapeutic margins in a novel preclinical model of retinitis pigmentosa.
J Neurosci
; 33(33): 13475-83, 2013 Aug 14.
Artigo
Inglês
| MEDLINE | ID: mdl-23946405